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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c6e7c31f297f0e8999bc5b4ebadac94812c81b33b05e5cdff271275bf5e4a8' 
  AND token = 'dwG196KcUIdIXP8z4wcgKBT5iPZnTjASHyo+yDMED8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}