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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4733af65100c9dfe2119c57245d2af62bf41d06b5bd27ba45d506266cf9a2de9' 
  AND token = 'r2kwNzLM8anUWO5GwTxzr1fiH/67XK9XJhqX9rmfH4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}