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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e579425fa4386e10e7a5e45ab5fa50b9b24a8bbbdf887e7f71a43b6ec55582' 
  AND token = 'TcIRk/xQX13YGK9Kpr2nn/WTHimgf1sWvBThUmto3JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}