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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e86f527c415aa741649f6a10a6830f6d17b6c248297d44552c3423b2cc5eb86' 
  AND token = 'CgMz0SFfbx4FLs/8oVUneq5WLbDglWzbl7ctuLEXkCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}