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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c8e599dd431bd9c046a90e2c911799f29a167b0e39403c3c10549319252f74' 
  AND token = 'm95N8VJF1hiNu3Q+OOmQkux/4hjJgwNmwzdJrpQ67Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}