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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09fe73bcdc512a30a9ad3776eb01d929d88fa5dd6be084f086f33515a9f7ffee' 
  AND token = 'Q9Sp/EWxoSFxJv/E0MlpFf259BOp89cfmUFN+SYS7VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}