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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe63b67a0ce9b58590d4d19fc661f7234546dcfde8888488578e9c9aea92add' 
  AND token = '5Y1QCC5nYBeBIIqrwL2ell7ApIs+BHWjIVeEfdPQAxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}