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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c5b243849de967ef6c849df2075a5ee21ecdac26600f08da4321af2914fcb3' 
  AND token = '+exMSlbMo8AN2SZqFNacQuIr9NUzuhnT4rueFV+y+4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}