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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3b927659b520d5e36184e123bc7ab5653ab9e6c4cf3b9fdeae907a897dd360' 
  AND token = 'Ad6VInvQs6VUQUmCBD+BmPSAnphdoJz4cQIdyh2l7Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}