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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec3e11af2fbae8b5e50032f4c8385022cded9f1d8f7b0bf96533afdc2af2070' 
  AND token = '3gBjxTH3tZlRGB0w9bmtIYDtNB+ph5J//IwDxah99rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}