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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446331d7c803ba6dfc1bb17737751b49633d3d3303e3743e29fb02d6753211f0' 
  AND token = '97/aJrbZMe+LJzJWeGUwE9RolLjVo8FAbZUwrDD7Drs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}