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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b124653a418cc465c333411c4e45887b05a4c82baebbdabcb5a72cbcd66d1b6' 
  AND token = '8Qv+s9s4vMf4knmCB689K9HulYlEXzBuszm8765tle4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}