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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d07c0d1080e03982bb5bdcb5a19700a0f71eac8ff3f668ebeb397a87dede49' 
  AND token = 'gxuBXTJ3bT/A/+8Bb5w19KUzypYQfjMN6QmnkNaHeuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}