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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b36ecc9f0e80bf4d1b4491cbf81186c4bafeff79a23607ef66573c86dc043681' 
  AND token = 'CEYTPtx+oSAjK5baiNkCU+zmyYs38e2hbRC94UuGV1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}