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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cda2bf38750bfb44530ec107929e6b420f778c1085d1542299492af4d82b020' 
  AND token = '+oQa9zK+1VBIikqMHeCTf/gZ5PE2erBzgTN5Ml055vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}