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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f5cce5db46c0434a7c4bd45d1980e649e352dfaf51ce99ba0b3615a1959c20' 
  AND token = 'NvtcOaxHVVsz8ffCEIKAanlmiuakrR/oHFvTA/m+Y+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}