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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '999089b5d1a6b699a1641da777b8e1057ee667e7dbf51493daab89c4bc36c287' 
  AND token = 'ePRDeJ0fj0N3l+qih1E15dVUMPISEGP4xjutY1gWY3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}