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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa495be0183f029706c448c96690064ed853e2b52d52100480c24eed9e04423c' 
  AND token = 'ZSLG3pH/dta3Gl6bAZcFoQtUvXmiE0U2T5VUAoKZMv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}