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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae2f566549fc64aac992dc7f1396e2d75215be1c061ce5cd982e2e5a8c9904f8' 
  AND token = 'CVR0b5BpZeMpQxQmdrpht5e/etyrnaAPfkkFyynY2e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}