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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0769e728eef8143838c62529d3d069021bd654fd6b33803fef6ff91536aebb' 
  AND token = 'Fx0Mciw5A8zXtna1aznbZImLJyeqy/LWCNSKuaSxLAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}