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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a7ce5af17391f04c0e993264dfa1f92b4fe47fe79de8943ac303d2b6529247' 
  AND token = 'jk2CWyy+pKKLXi2P8A1OIlY7kF5DOuPjDn7vhx9Necg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}