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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3ba3c9bd07cf072e08e065af59b9852612bdd380b35c41d9e1ee6979773044' 
  AND token = 'LdUo/oG4Rm05n04lKpVANCz6FqjNw7gnWup4EXnnsAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}