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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a29de8d6b995d3fdd1f4b2ab8bc4c24848b09c98a578c8e35b107c6244f49918' 
  AND token = 'Sx1VplRRpSNJn7K9aCWfX7H+t7YPK3lnQM6uXv3iM38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}