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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722cdace9d49619466879b585a631cd3413bcc768f3e3394326b753aafd39db6' 
  AND token = 'UpRnbbDP67WDHPp/CCAte3V1uCAeV/sB+bCjnBlzNDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}