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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a83d3582ce3ffd4cd853e2a49bbd9ae1a5f4646c59d21252dda9203c9598527' 
  AND token = 'OysW2g7U5YPXKmjEbjFbWcy6X/TyfIB4TbCR7tSCsSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}