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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b99d976daf972510f7fde967523dd72690e5d145c180f534589612ff5e247c' 
  AND token = 'n99N8aMcB/Er7RUo56pUykYbSaaiCkli2MFapTKoKKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}