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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cca45aa7fe4dad331d2d1e278790c7641c56ea84d38c68006f62f60d02e7d84' 
  AND token = 'XgIhp9lOqNWkbggm+Jl/Ck9L8mRfS2kSiBQO4utm4RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}