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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d15a09bb4b878b581641b243646e4aebbb016255f200bdeffe15796f30601a' 
  AND token = '3SxizXs9RRWpjBR6sSj1ivwYOAm6PFe/x+s+uQIbUUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}