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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd109d5bbe22b2b3fde0c8191ef55e498b1c5675c266e64a2b6c0d568abe570b4' 
  AND token = 'ginaR45FWmYKg+jEfm6g5ZqgcGdvexoTTZEYZeOLAaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}