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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5533dcc6a78710efc0ed9c8d32f1028d73d560b8e1c17898ea722c14998a71c2' 
  AND token = 'klgtkunTIybPKmcMFzksp8F30yP+WH9RwRQUS9Tc2dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}