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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34261d9bc1642260e9e0d631fe4d3dbe21d333e085598bf2002430cc0a566115' 
  AND token = 'IB4ChXudGApMViHNrWu9kWtYE+Mll8DnzC62Owflgak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}