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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ed93c76211fb52e4986082b475d26e23b35a8450aeb5fa72fa42a57c931936' 
  AND token = 'IPV9S+MeGO06p2COlc5n2Ne9bd/AuV4ZOd2SbJ0R85Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}