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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea22eeb32ebcf17948ea98d589bfe94a2436e75ebfc87b3785989adf6d7f92ad' 
  AND token = 'Ok/Lo6ZCKD6k6ynHPEWi0+YzCgFyX2v+rz2hK4n66us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}