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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadc8b66980df90801f9ca67b20d5aa7fb6fe5b691549f520bb3fd0e039c04e1' 
  AND token = 'X+Cj2kb5HHXsB1N5Yygqg/gY+fp7BceI5nrr0K86JX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}