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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c19a15604e5aff0cc1aaa909d6c7b16bb3671886ca59f153e4e0721629623a' 
  AND token = 'Uqn12ixxgFvjLwnvsB5LM0mYDHFb6nhmsG0mzAJ6oe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}