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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f646da76572db0fe48b5fb3f3099add2e08e9ce6c8edc2ade17f0663cca06b' 
  AND token = 'vIiEt8csF4YXhUhIX6GzhuoTIDyWPhEAR7YuRFS7LQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}