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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c0b5248eca1a7cc422a9fbc10a05f9d25cafb7fa1b1705d44d180cb00f8006d' 
  AND token = 'HEzCd0loNin4EeKSsXXIzKkn+BjcBiBEkODNRZbnpvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}