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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c0439f4f7c6dadc7f5be0b7448490e44e4232487d58cde0b99952e4dfde4637' 
  AND token = 'OHgg0N1ih4YIhUOBV6ueW05ONF8oTkHcW2u7u2bxkwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}