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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05333d4ac984bb139f2dedd0f9f9483bd515ee74341c5aa87f3468240b05e7a' 
  AND token = 'jE3ZA8dEKWOKQ9pMn1LKTxU2nAy+bgUtJtAhij+RjZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}