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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adae867dc264b1232e14257b6af23a53a1a4931b4148fa612fc6487e6ac9bd0d' 
  AND token = 'vJODR0OqtRcOB5B/ENzcYNMJkqkUfNBfp7bS0nGA9yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}