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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c973caa4a2f2478f58f36bba2b65c11104ae7cf9396e82767043448559a8de81' 
  AND token = 'y8HaDnM8QSvS0WDizlx5dHDXNPLe+Nra+fMVvn165V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}