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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd350668abf38b7468ef6a9fe185b4fd78838e68d8b19d0859b2a440750d4142f' 
  AND token = '+nfCss+NT5bt87qPrYNMHHsU2++BblLJNAXwi4URTEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}