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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0fcb6d6ed68e432ed46a4e66409d772090958cae12216191812c3a8d0469ed' 
  AND token = '5gZkIFVN46w9tC/ygjI5hoEf7A3vZNe0WBXXbQ75Mo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}