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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0ec0cbaa8ce93ebad6ad0c479a7276f0df12a5b30e4c64c9a7b74e04474af8' 
  AND token = 'vtI1v3p7S8uWJ8/08d4JxCbtgVYRKb3m1jjPb2LHEFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}