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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed9f80ee9a9a73af2c3bcdadc2819821102cfa28411e9a240f645b35462a3fc' 
  AND token = '2ItbZIBjADwAfGIiIXfJB2C4R4+Q/hgg1tBQbp3ll7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}