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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '706c5afbd7930e97fb1b6debfda0492b54132ada12ebd2b44f29c5981d8ca0d1' 
  AND token = 'JibEXKxyvFzDYJFdDNyACzYnNzVQ2Fgrx4E5F2wvm6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}