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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09ce0c4ba8e54f64fa4257723452f02289d980003a4e7dd98ce4da89f6566ba1' 
  AND token = 'gqrDyO6Aj/NA4ZrGN2KM2Fdu99OBr1pPlaa4iFVm3Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}