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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fabbe81c681333f47fdcd2d35c87104f66193332395e5e9f3209bc89a3e14c9' 
  AND token = 'RpvVBb6xsEIEVCRTTNHAH3jwiv6dpC5Z2F6m/d+8DxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}