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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e505cecefc1d878d9cff370071f6d8f999fcc03fbe9246b70957d8eebddebc36' 
  AND token = 'Ghl7HZFr8AgoF7ZS3WOW3aOMhvUI1urA77iHayPPH0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}