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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5683069f08b9b8321480384c77fb706c4a55535bb0980d0fa9211375f766c399' 
  AND token = 't7vPpExx4I60yGY8Ho56rBjxa2IvuwjIB7d3p+qsXwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}